Cancer Heterogeneity and Plasticity

ISSN 2818-7792
Free Publication in 2025

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About This Journal
Cancer Heterogeneity and Plasticity (ISSN 2818-7792) is an international, peer-reviewed, Open Access (OA) journal dedicated to showcasing outstanding original research articles, reviews, and perspectives spanning the dynamic realm of cancer cell heterogeneity and adaptability and the complexities within their microenvironments. Its scope encompasses a wide spectrum of topics, including but not limited to the elucidation of evolutionary relationship of cancer cell subpopulations (i.e., heterogeneity), molecular mechanisms driving cancer cell plasticity (e.g., epithelial-mesenchymal transition or EMT), epigenetic underpinnings of cancer cell reprogramming (e.g., treatment-induced neuroendocrine (NE) transdifferentiation), and the influence of the tumor microenvironment (TME) on cancer cell dynamics. It extends to embrace studies exploring the impact of the microenvironment and systemic host factors (e.g., hormones, growth factors, inflammatory cytokines, and nerves) on cancer progression, therapeutic resistance, cancer cell dissemination and dormancy, metastasis, and the development of innovative targeted and combinatorial therapies.
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About Editor-in-Chief
Dean G. Tang

Professor and Chair, Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center (RPCCC), USA

Dean G. Tang is currently Professor and Chair of Department of Pharmacology & Therapeutics at the Roswell Park Comprehensive Cancer Center in Buffalo, NY. He also holds the George Decker Endowed Chair in Developmental Therapeutics. Trained as a Pathologist, Dr. Tang obtained his PhD in Cancer Biology in 1994 from Wayne State University (Detroit, MI, USA). In 1998-2000, Dean pursued a Burroughs-Wellcome senior post-doctoral fellowship with Dr. Martin Raff at the MRC LMCB (University College London, UK) studying stem/progenitor cell development and plasticity. In June 2000, Dr. Tang joined the University of Texas M.D Anderson Cancer Center as a faculty member. After working at the M.D Anderson for 16 years, Dr. Tang was recruited to Roswell Park in June of 2016 to Chair the Department of Pharmacology & Therapeutics and Co-Lead the CCSG Developmental Therapeutic (DT) Program. He's also the Chair of the Experimental Therapeutic (ET) Graduate Program.
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Latest Articles
Review

Astrocyte plasticity shapes brain metastasis progression through tumor-astrocyte crosstalk

Rupleen Kaur, Nalin Gupta, Andrew Dhawan

Cancer Heterogeneity and Plasticity https://doi.org/10.47248/chp2502010002

Received: Oct 30, 2024 | Accepted: Dec 13, 2024 | Published: Jan 13, 2025
Review

Molecular mechanisms driving lineage plasticity in prostate cancer: NANOG and beyond

Hamed Maasoumyhaghighi, Mansoureh Nouri, Jinghui Liu, Xiaoqi Liu

Cancer Heterogeneity and Plasticity https://doi.org/10.47248/chp2502010001

Received: Nov 1, 2024 | Accepted: Dec 9, 2024 | Published: Dec 27, 2024
Editorial

Cancer Heterogeneity and Plasticity: 2024 in Review

Dean Tang

Cancer Heterogeneity and Plasticity https://doi.org/10.47248/chp2401020013

Received: Dec 23, 2024 | Accepted: Dec 23, 2024 | Published: Dec 24, 2024
Editorial

Acknowledgement to Reviewers of Cancer Heterogeneity and Plasticity in 2024

CHP Editorial Office

Cancer Heterogeneity and Plasticity https://doi.org/10.47248/chp2401020012

Received: Dec 22, 2024 | Accepted: Dec 22, 2024 | Published: Dec 22, 2024
Review

Heterogeneity of tumor biophysical properties and their potential role as prognostic markers

Anja Madleine Markl, Daniel Nieder, Diana Isabel Sandoval-Bojorquez, Anna Taubenberger, Jean-François Berret, Artur Yakimovich, Eduardo Sergio Oliveros-Mata, Larysa Baraban, Anna Dubrovska

Cancer Heterogeneity and Plasticity https://doi.org/10.47248/chp2401020011

Received: Oct 15, 2024 | Accepted: Nov 28, 2024 | Published: Dec 19, 2024
Review

The molecular determinants of phenotypic plasticity in homeostasis and neoplasia

Bradley Balk, David W. Goodrich

Cancer Heterogeneity and Plasticity https://doi.org/10.47248/chp2401020010

Received: Oct 10, 2024 | Accepted: Nov 14, 2024 | Published: Dec 13, 2024
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