I am currently working as Distinguished Professor at the Institute for Genetic Medicine, Hokkaido University. In my lab, we have been studying about stem cell-like glioblastoma (GBM) cells, also known as GBM-stem cells or GBM-initiating cells (GICs), by generating mouse GICs and using patient-derived GICs. We have identified many factors involved in GIC characters and functions and are now developing new therapeutic methods including ADC and recombinant viruses. In parallel, we have been also investigating molecular mechanism of novel factors involved in Alzheimer’s disease and are developing new diagnosis and therapeutic methods. I have been serving as a council member of the Japanese Association for Molecular Target Therapy of Cancer and Hokkaido Cancer Association.